Regeneron Pharmacueticals Inc v Genentech Inc
Kim 1992 did not anticipate the patent because it did not disclose or enable the claimed therapeutic use of VEGF antagonists for non-neoplastic diseases; it merely suggested potential. The invention was not obvious because the skilled person would not have had a fair expectation of success in using anti-VEGF therapy for the claimed diseases based on Kim 1992 and the common general knowledge. The patent was sufficiently enabled for the claimed scope, as the evidence supported a reasonable prediction that anti-VEGF therapy would work for non-neoplastic diseases characterized by excessive angiogenesis. VTE falls within the scope of the claims as an isolated VEGF receptor variant. The patent...
- Parties
- Claimant: Regeneron Pharmaceuticals Inc; Claimant: Bayer Pharma AG; Defendant: Genentech Inc
- Jurisdiction
- England and Wales
- Judgment Date
- 22 March 2012
- Procedural Posture
- Patent Revocation and Non Infringement Claim / First Instance Judgment
- Outcome
- Patent upheld and found infringed
- Legal Topics
- Patent Validity, Novelty, Inventive Step (obviousness), Sufficiency, Infringement, Therapeutic Use Claims
Case Brief
Summary, issues, holding and outcome
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Parties
Regeneron Pharmaceuticals Inc
Claimant
Bayer Pharma AG
Claimant
Genentech Inc
Defendant
Procedural Posture
Patent Revocation and Non Infringement Claim / First Instance Judgment
Legal Issues
- 1 Whether European Patent (UK) No 1 238 986 is invalid for lack of novelty, inventive step, or insufficiency
- 2 Whether the patent is infringed by VEGF Trap Eye (VTE)
Ratio Decidendi
Kim 1992 did not anticipate the patent because it did not disclose or enable the claimed therapeutic use of VEGF antagonists for non-neoplastic diseases; it merely suggested potential. The invention was not obvious because the skilled person would not have had a fair expectation of success in using anti-VEGF therapy for the claimed diseases based on Kim 1992 and the common general knowledge. The patent was sufficiently enabled for the claimed scope, as the evidence supported a reasonable prediction that anti-VEGF therapy would work for non-neoplastic diseases characterized by excessive angiogenesis. VTE falls within the scope of the claims as an isolated VEGF receptor variant. The patent...
Court Disposition
Patent upheld and found infringed
Orders
- Declaration that European Patent (UK) No 1 238 986 is valid
- Declaration that VEGF Trap Eye infringes the patent
Full Case Text
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